GLP-1 Medication Comparison: Nigeria
Compare Ozempic, Mounjaro, Wegovy, and other GLP-1 medications. Find the best weight loss medication for your goals and budget in Nigeria.
Quick Answer: Which GLP-1 is Best?
For maximum weight loss: Tirzepatide (Mounjaro/Zepbound) - up to 22.5% body weight loss
Most proven track record: Semaglutide (Ozempic/Wegovy) - 12-15% weight loss, millions of users
Best value in Nigeria: Generic semaglutide or tirzepatide - same results, fraction of cost
GLP-1 Medication Comparison Chart
Complete side-by-side comparison of all major GLP-1 and related weight loss medications.
| Medication | Active Ingredient | Mechanism | Avg Weight Loss | Dosing | Nigeria Availability |
|---|---|---|---|---|---|
| Ozempic | Semaglutide | GLP-1 agonist | 12-15% | Weekly injection | Generic available |
| Wegovy | Semaglutide | GLP-1 agonist | 15-16% | Weekly injection | Generic available |
| Mounjaro | Tirzepatide | GLP-1/GIP dual | Up to 22.5% | Weekly injection | Generic available |
| Zepbound | Tirzepatide | GLP-1/GIP dual | Up to 22.5% | Weekly injection | Generic available |
| Retatrutide | Retatrutide | GLP-1/GIP/Glucagon | Up to 24% | Weekly injection | Coming soon |
| Rybelsus | Semaglutide | GLP-1 agonist | 8-12% | Daily oral tablet | Limited |
* Weight loss percentages from clinical trials. Individual results may vary based on diet, exercise, and adherence.
Semaglutide vs Tirzepatide: Head-to-Head
Semaglutide
Ozempic, Wegovy, Rybelsus
- Mechanism: GLP-1 receptor agonist only
- Weight loss: 12-16% average
- Track record: FDA approved 2017, millions of users
- Oral option: Rybelsus tablets available
- Heart benefits: Proven cardiovascular protection
Tirzepatide
Mounjaro, Zepbound
- Mechanism: Dual GLP-1 + GIP receptor agonist
- Weight loss: Up to 22.5% (highest)
- Track record: FDA approved 2022, newer but impressive
- Blood sugar: Superior A1C reduction for diabetics
- Best for: Maximum weight loss goals
Head-to-Head Clinical Trial Results
The SURMOUNT-5 trial directly compared tirzepatide vs semaglutide for weight loss in adults without diabetes:
* Results from 72-week SURMOUNT-5 trial. Both groups also followed diet and exercise recommendations.
Brand vs Generic: What You Need to Know
The Truth About Generics
Generic medications contain the exact same active ingredient as their brand-name counterparts. The difference is price - brand names like Ozempic and Mounjaro include massive marketing budgets and brand premiums in their cost.
- Generic semaglutide = Same molecule as Ozempic/Wegovy
- Generic tirzepatide = Same molecule as Mounjaro/Zepbound
- Identical weight loss results when properly dosed
- 60-80% cost savings with generics
Pricing in Nigeria
| Medication Type | Monthly Cost (Est.) | Notes |
|---|---|---|
| Brand Ozempic (if available) | N500,000+ | Rare in Nigeria, often out of stock |
| Brand Mounjaro (if available) | N600,000+ | Very limited availability |
| Generic Semaglutide (NaijaBody) | N150,000 - N200,000 | Same active ingredient, reliable supply |
| Generic Tirzepatide (NaijaBody) | N180,000 - N220,000 | Same active ingredient, reliable supply |
* Prices are estimates and may vary. Contact us for current pricing.
How to Choose the Right GLP-1 Medication
1. Your Weight Loss Goals
Semaglutide is well-proven and may be more than enough for your goals.
Tirzepatide typically produces greater results and may be worth the investment.
2. Your Medical History
Both work well. Tirzepatide shows superior blood sugar control in trials.
Semaglutide has proven cardiovascular benefits. Tirzepatide studies ongoing.
3. Side Effect Tolerance
Both medications have similar side effect profiles (nausea, digestive issues). These typically improve over 2-4 weeks. Start with low doses and titrate slowly to minimize side effects.
Pro tip: Some people who don't tolerate semaglutide well do better on tirzepatide, and vice versa. If one doesn't work for you, the other might.
4. Your Budget
Both generic semaglutide and tirzepatide are similarly priced through NaijaBody. The choice should be based on your goals and medical needs, not cost.
Our Recommendation
For first-time users: Start with semaglutide. It has a longer track record, proven cardiovascular benefits, and is highly effective for most people.
For maximum results: Consider tirzepatide if you have significant weight to lose (BMI 35+) or haven't achieved your goals with semaglutide.
Not sure? Message us for personalized guidance based on your specific situation.
Side Effects: What to Expect
Both semaglutide and tirzepatide have similar side effect profiles. Most side effects are gastrointestinal and improve over time.
Common (Usually Temporary)
- Nausea - most common in first 2-4 weeks
- Diarrhea or constipation
- Reduced appetite (this is also the goal!)
- Stomach discomfort or bloating
- Fatigue during adjustment period
- Injection site reactions
Seek Medical Attention For
- Severe, persistent stomach pain
- Signs of pancreatitis
- Vision changes
- Severe allergic reactions
- Symptoms of gallbladder problems
- Signs of thyroid tumors
Tips to Minimize Side Effects
- Start low, go slow: Begin with the lowest dose and increase gradually
- Eat smaller meals: Avoid large portions that can worsen nausea
- Avoid fatty foods: High-fat meals can increase digestive discomfort
- Stay hydrated: Drink plenty of water throughout the day
Frequently Asked Questions
Tirzepatide (Mounjaro/Zepbound) shows the highest weight loss in clinical trials at up to 22.5%. Semaglutide (Ozempic/Wegovy) averages 12-15% weight loss. Both are available through NaijaBody in Nigeria as pharmaceutical-grade generics.
Ozempic contains semaglutide (GLP-1 agonist) while Mounjaro contains tirzepatide (dual GLP-1/GIP agonist). Mounjaro's dual action typically produces greater weight loss (22.5% vs 15%) but both are effective. The main practical difference is that tirzepatide tends to produce more weight loss in clinical trials.
Yes! NaijaBody supplies pharmaceutical-grade generic semaglutide and tirzepatide in Nigeria. These contain the same active ingredients as brand-name medications at a fraction of the cost. We deliver nationwide to Lagos, Abuja, Port Harcourt, and all major cities.
Generic semaglutide starts from around N150,000-200,000 per month through NaijaBody. Brand-name Ozempic can cost N500,000+ when available. Generic tirzepatide is priced similarly to generic semaglutide. Contact us for current pricing.
Both contain semaglutide. Ozempic is approved for diabetes (max 2mg) while Wegovy is approved for weight loss (max 2.4mg). The higher Wegovy dose produces better weight loss results. With generic semaglutide, you can use either dosing schedule.
Clinical trials show Mounjaro (tirzepatide) produces greater average weight loss than Ozempic (semaglutide) - up to 22.5% vs 15%. However, individual results vary significantly and both medications are highly effective. Some people respond better to one than the other.
Retatrutide is a next-generation triple agonist (GLP-1/GIP/Glucagon) from Eli Lilly showing up to 24% weight loss in Phase 2 trials. It's currently in Phase 3 clinical trials and is expected to be FDA approved in 2025-2026. We'll offer it when available.
Common side effects include nausea, diarrhea, constipation, and reduced appetite. These are usually mild and improve over the first few weeks. Starting with low doses and titrating slowly minimizes side effects. Serious side effects are rare but include pancreatitis and gallbladder issues.
Yes, you can switch between medications. Many people switch from semaglutide to tirzepatide to achieve greater weight loss. When switching, you typically start tirzepatide at a low dose even if you were on a higher semaglutide dose. Contact us for guidance on transitioning.
We deliver nationwide across Nigeria using cold chain logistics to maintain medication potency. Deliveries typically take 2-5 days depending on location. Major cities like Lagos and Abuja often receive same-day or next-day delivery. All packages are discreetly packaged.
Ready to Start Your Weight Loss Journey?
Get pharmaceutical-grade semaglutide or tirzepatide delivered to your door in Nigeria. Same active ingredients as Ozempic and Mounjaro at a fraction of the cost.
Learn More
Ozempic in Nigeria
Complete guide to semaglutide: how it works, dosing, side effects, and availability.
Mounjaro in Nigeria
Everything about tirzepatide: the dual-action medication with superior weight loss results.
Weight Loss Guide
Tips for maximizing your results with GLP-1 medications in Nigeria.